Objawy choroby Parkinsona są przede wszystkim skutkiem niedoboru dopaminy w prążkowiu, dlatego metody leczenia skupiają się głównie na zwiększeniu dostępności tego neuroprzekaźnika w OUN. Najskuteczniejszym lekiem, przez niektórych traktowanym jako „złoty standard” w terapii ch.P. jest lewodopa (L-dopa) - bezpośredni prekursor dopaminy, przekraczający barierę krew-mózg i przekształcany przez dekarboksylazę do dopaminy.
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